Ipamorelin itself doesnt usually cause true weight gain, but some people experience temporary water retention or increased appetite that can make the scale fluctuate.
I recommend reviewing my article on low stomach acid and if you think you might have low stomach acid, try the recommended Rootcology supplement, Betaine with Pepsin (this was a game-changer for me!)
Metabolic consequences of intrauterine growth retardation
HS induces S-sulfhydration of MuRF1 at the Cys44 site, inhibiting its E3 ligase activity, reducing SERCA2a ubiquitination and degradation, thereby restoring SERCA2a function, lowering intracellular Ca 2+ , and enhancing contractile performance (Peng et al., 2022)
Major increase in microbiota-dependent proatherogenic metabolite TMAO one year after bariatric surgery